Travel to Agathonissi
In spite of the fact that Agathonissi lies a little out-of-the-way and seems to be in a world of its own, it is amazingly easy to travel here. However, it is difficult to travel from the island, but it do not depends on bad ferry connections, it depends on the fact that you do not want to leave the island.
BY INTERNATIONAL FLIGHTS
The absolutely easiest way is to go by air to Samos. From the airport of Samos, take a taxi to Pythagorion (4 km) and from there, go on by ferry to Agathonissi. There are usually plenty of available taxis outside the airport terminal. Ferry tickets can be bought in any of the travel agencies on the main street in Pythagorion, or at the ticket kiosk in the port.
Another option is to go by air to Kos. From Kos' airport, take a taxi to Kos town, and travel on by ferry to Agathonissi.
BY DOMESTIC FLIGHTS
The nearest domestic airports is at Leros and Samos.
Nisos Kalymnos in the port of Agathonissi.
The lifeline in this part of the Greek archipelago is named Nisos Kalymnos. Nisos Kalymnos is a small car ferry with its home port on Kalymnos, she sails the same route all year around: Kalymnos, Leros, Lipsi, Patmos, Arki, Agathonissi and Samos, where she turns and sails the same way back.
Do not expect that Nisos Kalymnos runs on schedule, but you can bet that she sails in (almost) any weather. It takes a lot to make Nisos Kalymnos to stay in port.
The catamaran Dodekanisos Seaways and Leros Sea Ways also
operates on Agathonissi a few days a week.
The small travel agency at Agathonissi.